درصد گرفتگی شریان کرونر با سطح هموسیستین در زنان یائسه که تحت جراحی پیوند شریان کرونر هستند مرتبط است.
Atherosclerosis is one of the common causes of morbidity and mortality, especially in postmenopausal women. Homocysteine, a sulfur-containing amino acid product of methionine metabolism, may play an important role in the development of cardiovascular diseases. Homocysteine increases especially after menopause. Previous studies have shown an association of hyperhomocysteinemia with cardiovascular disease; however, the role of hyperhomocysteinemia in the progression of coronary artery disease is still unknown. This study was designed to evaluate the relationship between intra-operative grading of coronary artery atherosclerosis and homocysteine level in postmenopausal women who were candidates for off-pump coronary bypass graft surgery (CABG). According to our findings, homocysteine level increases in post-menopausal women that can be an important risk factor for atherosclerosis and cardiovascular diseases.